Pathology EMQ template.

Name:

Candidate number:

Theme: Introduction to Leukaemia

 

OPTION LIST

 

A

1

I

15

B

2

J

20

C

3

K

25

D

6

L

30

E

7

M

94

F

8

N

96

G

9

O

98

H

10

P

100

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A type __ mutation leads to uncontrolled cell proliferation.

 

 

2. The JAK2 V617F mutation is found in __% of cases of polycythaemia rubra vera.

 

 

3. The translocation t(__;22) leads to the creation of the fusion gene BCR-ABL.

 

 

4. A proportion of blast cells of >__% gives a diagnosis of acute leukaemia.

 

 

5. The translocation t(__;14) is the commonest mutation seen in Burkitt lymphoma.

 

 

ANSWERS

1. A

2. O

3. G

4. J

5. F