Pathology EMQ

Name:

Candidate number:

Theme: Paediatric Haematology

 

OPTION LIST

 

A	Alloimmune thrombocytopenic purpura	I	Haemophilia B
B	Alpha thalassaemia	J	Henoch-Schönlein Purpura
C	Autoimmune thrombocytopenic purpura	K	Hereditary spherocytosis
D	Beta thalassaemia major	L	Non-hereditary spherocytosis
E	Diamond-Blackfan anaemia	M	Sickle cell disease
F	Fanconi’s anaemia	N	Sickle cell HbD disease
G	G6PD deficiency	O	Sickle cell trait
H	Haemophilia A	P	TAR syndrome

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A neonate is born clinically jaundiced. Red blood cells are osmotically fragile and a peripheral blood film shows that they are markedly small, without a central zone of pallor.

 

2. A neonate is born with widespread petechiae and purpurae, but is otherwise well. The WCC and Hb are normal, and the peripheral blood film does not show blast cells.

 

3. A routine heel prick test on a neonate born in Chandigarh identifies Hb S and another variant Hb.

 

4. A neonate is born in Bangkok Hospital at 28 weeks severely oedematous and pale, with a massive placenta, and dies within an hour of birth.

 

5. A neonate is born with shortened arms; thumbs and digits are present. Blood tests reveal a thrombocytopenia.

 

ANSWERS

1. K

2. A

3. N

4. B

5. P