Pathology EMQ template.

Name: Natasha Castellino            

Candidate number:

Theme: Chronic Lymphocytic Leukaemia

 

OPTION LIST

 

A	ABVD Chemotherapy	I	Splenectomy
B	Campath	J	Stem Cell Transplantation
C	FCR Chemotherapy	K	‘Watchful Waiting’
D	Intravenous Immunoglobulin	L
E	Oral Chlorambucil	M
F	Prednisolone	N
G	Radiotherapy	O
H	R-CHOP	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. 72-year-old Mr. X has an FBC showing a lymphocytosis >5x10⁹/l, Hb 14g/dl and platelets 200x10⁹/l. Blood film shows lymphocyte morphology consistent with CLL, but examination of Mr. X is unremarkable. Choose the appropriate management for this patient.

 

2. Choose the appropriate management for CLL patients who are refractory to chemotherapy

 

3. A 55-year-old patient has hepatosplenomegaly and lymphadenopathy, Binet stage B. He does not have a 17q mutation. Choose the appropriate management for this patient.

 

4. 80-year-old female, presents with increasing tiredness and fever. On examination, there are enlarged lymph nodes in the neck and axilla. Choose the appropriate management for this patient.

 

5. Can be used in combination with chemotherapy, and to treat CLL complications of autoimmune haemolytic anaemia or thrombocytopenia.

 

 

ANSWERS

1. K

2. B

3. C

4. E

5. F