Pathology EMQ template.

Name: Florence Chamberlain      

Theme: Myeloproliferative Disorders

 

OPTION LIST

 

A	Myeloblasts	I	Dasatinib
B	Lymphocyte	J	Blasts
C	Imatinib	K	t(12;21)
D	Neutrophils	L	Metamyelocytes
E	t(9;22)	M	t(9;12)
F	Nilotinib	N	Eosinophils
G	Leukocytes	O	Donor lymphocyte infusion
H	Basophils	P	Stem cell transplant

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1.    The chromosomal translocation seen in 90-95% of CML cases

 

2. In CML large numbers of differentiated ________ are present in the peripheral blood plus an excess of myelocytes (fill in the blank space)

 

 

3. This cell has a prominent nucleolus and primary granules

 

 

4. The first line therapy used commonly to help control the proliferation of chronic phase cells in CML

 

 

5. The next therapy used following resistance to tyrosine kinase inhibitors

 

 

 

ANSWERS

1. E

2. D

3. A

4. C

5. P