Pathology EMQ template.

Name: Reuben Gibbons

Theme: Haemolytic anaemias

 

OPTION LIST

 

A	α-Thalassaemia	I	Sickle cell anaemia
B	β-thalassameia major	J	Spherocytosis
C	β-Thalassaemia minor	K	Transfusion reaction
D	Glucose-6-phosphate dehydrogenase deficiency	L
E	Malaria	M
F	Paroxysmal nocturnal haemoglobinuria	N
G	Penicillin induced haemolytic anaemia	O
H	Pyruvate kinase deficiency	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1.  A child presents with jaundice and splenomegaly and jaundice and is found to be mildly anaemic. Red blood cells are shown to be fragile in hypotonic solutions.

 

 

2.  First urine sample of the day found darker relative to other samples and urinary haemosiderin positive. Cellular immunotyping reveals altered GPI.

 

 

3. This condition is mainly asymptomatic but susceptible to oxidative crisis due to reduced gluthione production. Precipitated by drugs such as aspirin.

 

 

4. A patient presents having experienced abrupt  fever and rigors, on examination there is anaemia and hepatosplenomegaly. Patient has been on holiday recently.

 

 

5. Asymtomatic heterozygous condition with mild anaemia and low mean cell volume and mean corpuscular haemoglobin.

 

 

                                                                                                  

ANSWERS

1. E

2. D

3. C

4. J

5. A