Pathology EMQ

Name: Louise Glanvill         

Theme: Herpes and retroviral infections

 

OPTION LIST

 

A	Vitamin K deficiency	I	HIV2
B	HIV clade A	J	HIV clade D
C	Plasma HIV- Ab	K	Protease inhibitor side effects
D	Factor VIII deficiency	L	HIV clade B
E	Plasma HIV-RNA	M	HHV8
F	HIV1	N	HHV4
G	Subhyaloid haemorrhage	O	HHV5
H	Plasma p24-Ag	P	Retinoblastoma

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A 46 year old married man who has recently developed a penchant for “swinging” presents with malaise, myalgia, pharyngitis and a maculopapular rash. What test would most likely NOT confirm or rule out your primary differential diagnosis?

 

 

 

2. Associated with Post Transplant Lymphoproliferative Syndrome involving uncontrolled proliferation of B cell lymphocytes.

 

 

 

3. Associated with the worst prognosis in terms of disease progression to AIDS.

 

 

 

4. A 52 year old man presents with bruise like lesions which have progressed to purple grape like lesions. On taking a thorough history you ascertain that he received a kidney transplant 6 years ago. What is the likely cause of these lesions?

 

 

 

5. A 55 year old man with long term AIDS presents with decreased visual acuity. Fundoscopy reveals characteristic “mozzarella pizza” signs.  What is the most likely cause?

 

 

 

 

ANSWERS

1.  C

2.  N

3.  L

4.  M

5.  O