Pathology EMQ template.

Name: Chris Hogan

Theme: Leukaemia

 

OPTION LIST

 

A	Acute lymphocytic leukaemia	I	Prolymphocytic leukaemia
B	Acute myelogenous leukaemia	J
C	Adult T-cell leukaemia/lymphoma	K
D	Aplastic aneamia	L
E	Chronic lymphocytic leukaemia	M
F	Chronic myelogenous leukemia	N
G	Hairy cell leukaemia	O
H	Multiple myeloma	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. The most common malignancy diagnosed in children.

 

 

2. Initial treatment of this malignancy is with the BCR-ABL tyrosine kinase inhibitor, inmatinib.

 

 

3. Smudge cells, seen on blood film, are pathognomonic for this disease

 

 

4. Rare malignant disorder of mature T-cells, caused by infection by the retrovirus HTLV-1. Can present as a leukaemia or as a lymphoma. Median survival is less than one year.

 

 

5. The accumulation of malignant, undifferentiated blast cells in the bone marrow often results in bone marrow failure, which is the leading cause of death in this disease. Leukaemic blast cells with intracellular Auer rods can be seen on blood film.

 

 

 

ANSWERS

1. A

2. F

3. E

4. C

5. B