Pathology EMQ template.

Name: Varsha Kadaba

Theme: Lymphoma

 

OPTION LIST

 

A	Burkitt's Lymphoma	I
B	Diffuse Large Cell Lymphoma	J
C	Follicular Lymphoma	K
D	Hodgkin's Lymphoma	L
E	Lymphoblastic Lymphoma	M
F	Mantle Cell Lymphoma	N
G	Multiple Myeloma	O
H	Small Lymphocytic Lymphoma	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. 20 year old man presents with a painless neck lump. He admits to having suffered from a recent viral infection. Blood smear shows a binucleate giant cell. Further analysis reveals CD30+ and CD15+ cell markers.

 

2. 55 year old man is being investigated after recurrent infections. Serum protein electrophoresis showed a monoclonal immunoglobulin spike and blood smear showed rouleaux formation.

 

3. 64 year old man presents with a painless lump in his axilla. On further questioning, he admits to unexplained 10kg weight loss in the last 3 months. Immunophenotype processing shows CD5+ and a translocation of t(11;14) is present.

 

4. 10 year old boy recently emigrated from Africa presents with a lump on his jaw. Genetic profiling shows a translocation of t(8;14). Microscopy shows a ‘starry-sky’ appearance.  

 

5. 70 year old man presents with a painless neck lump. He has a history of joint pains and dry eyes. There is a translocation of t(14;18).

 

 

 

ANSWERS

1. D

2. G

3. F

4. A

5. C