Pathology EMQ template.

Name: Kimmee Khan 

Theme: Metabolic bone histopathology

 

OPTION LIST

 

A	Baker's cyst	I	Renal Osteodystrophy
B	Hypercalcaemia	J	Ricket’s disease
C	Hyperparathyroidism	K	Vitamin D Toxicity
D	Multiple Myeloma	L
E	Osteogenesis Imperfecta	M
F	Osteomalacia	N
G	Osteoporosis	O
H	Pagets disease	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. 54 year old lady with a past medical history of multiple epileptic fits presents with back pain following a fit. Imaging shows fractures and bone biopsy shows abnormally large holes in the bone architecture.

 

 

2. 10 year old boy presents with bone pain in his legs. Imaging shows widened costochondrial junctions and horizontal fractures in Looser’s zone. Bone biopsy shows bone that is undermineralised.

 

 

3. 50 year old gentleman with past medical history of acute pancreatitis and low mood presents with fractured fingers after accidentally closing a door on his hand. Imaging shows areas of bone reabsorption and bone biopsy shows that these areas are filled with osteocytes.

 

 

4. 45 year old lady presents with back pain. Imaging shows nerve compression. She has a family history of similar back pain and genotyping shows a mutation in 5q35-qter-sequestosome 1 gene.

 

 

5. 60 year old lady with a compression fracture in her spine at level T11-T12. She has a past medical history of severe asthma for which she takes medication regularly.

 

 

 

ANSWERS

1. G

2. J

3. C

4. H

5. G