Pathology EMQ

Name: Ahmed Latif

Theme: Myelodysplastic Syndromes

 

OPTION LIST

 

A	Aplastic Anaemia	I	Multiple Myeloma
B	Refractory anaemia with excess blasts in transformation (RAEB-t)	J	5q Deletion Syndrome
C	Hodgkins Lymphoma	K	Refractory anaemia with excess blasts II (RAEB-II)
D	Sideroblastic Anaemia	L	Refractory cytopenia of childhood
E	Chronic Myeloid Leukemia	M	Refractory anaemia with excess blasts I (RAEB-I)
F	Chronic myelomonocytic leukaemia	N	None of the above
G	Fanconi Anaemia	O
H	Acute Myelomonocytic Leukemia	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1)         A 50 year old man, known to be an alcohol abuser presents with shortness of breath. He has a haemoglobin of 8.7g/dl and sideroblasts in his bone marrow aspirate

 

2)         A 62 year old female present with shortness of breath. Her blood film shows a macrocytic anaemia with thrombocytosis and the presence of megakaryocytes

 

3)         A 70 year old patient with weakness and shortness of breath is diagnosed with macrocytic anaemia with pancytopenia. Bone Marrow aspirate shows 17% blasts

 

4)         A 68 year old lady presents with swollen gums and easy bruising. A bone marrow biopsy shows Auer Rods

 

5)         A 73 year old lady with breathlessness, easy bruising and recurrent infections is discovered to have macrocytic anaemia. Her bone marrow shows 6% blasts

 

 

ANSWERS

1. D

2. J

3. K

4. H

5. M