Pathology EMQ template.

Name: Niraj Nanavati          

Candidate number:

Theme: Plasma Proteins

 

OPTION LIST

 

A	CRP	I	Thyroxine-Binding Globulin
B	α-1 anti-trypsin	J	Prothrombin
C	Transferrin	K	Low-Density Lipoprotein
D	Caeruloplasmin	L	Albumin
E	Ferritin	M	Fibrinogen
F	Haptoglobin	N	High-Density Lipoprotein
G	β2-microglobulin	O	Mannose-Binding Lectin
H	Bence Jones Protein	P	IgE

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A 64 year old African Male presents with a 2 year history of spinal pain which worsens on activity. He is found to have increased plasma cells on bone marrow biopsy. Which protein, found by electrophoresis is suggestive of his condition?

 

 

2. A 20 year old male presents with insidious onset neurological and psychiatric symptoms. He also has clinical features of chronic liver disease. Which plasma protein is abnormally low in this condition?

 

 

3. Which Plasma Protein is characteristically low in Iron Deficiency, but high in Anaemia of Chronic Disease? 

 

 

4. A 34 year old female has been told by her GP she has ‘asthma.’ She gets recurrent chest infections, but they never seem to respond to treatment. She smoked socially from 18-24. She also appears to have signs of chronic liver disease. What may she have a deficiency in?

 

 

5. Which Plasma Protein has an important role in innate immunity by forming a complex with MASP, activating the complement system?

 

 

 

ANSWERS

1. H

2. D

3. E

4. B

5. O