Pathology EMQ template.

Name: Mohsin Salahuddin

Theme: Transplantation

 

OPTION LIST

 

A	Acute rejection	I	Renal carcinoma
B	Azathioprine	J	Ureteric stones
C	Chronic rejection	K
D	Cyclosporin	L
E	Graft-versus host disease	M
F	Hyperacute rejection	N
G	Prednisolone	O
H	Pylonephritis	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Side effects of this drug include gingival hyperplasia, convulsions and peptic ulcers

 

 

2.  A 60 year old woman presents 2 weeks after a kidney transplant.  She has a temperature of 38.4C, a heart rate of 110bpm, and complains of pain over right iliac fossa. Investigations show: Na 135mmol/l, K 6.1mmol/l, urea 19mmol/l and creatinine 500umol/l.  Ultrasound shows normal renal pelvis. 

 

 

3. Following bone marrow transplantation T cells in transplanted marrow mount a cell-mediated response against recipient antigens.

 

 

4. Purine analogue immunosuppressive drug used to prevent organ rejection

 

 

5. A 60 year old man presents for a follow up to clinic post renal transplantation 2 years ago.  He has a bp of 135/90, proteinuria, and investigations show: Na 135mmol/l, K 5mmol/l, urea 15mmol/l, creatinine 220umol/l.

 

 

 

ANSWERS

1. D

2. A

3.  E

4. B

5. C