Pathology EMQ template.

Name:

Theme:

 

OPTION LIST

 

A	CD4+ T-cells	I	Cyclophosphamide
B	CD8+ T-cells	J	Belatacept
C	Antibodies	K	Mycophenolate mofetil
D	B-Cells	L	Daclizumab
E	Methotrexate	M
F	Coricosteriods	N
G	Cyclosporine	O
H	Azathioprine	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

 

1. Transplantation of donor tissues across incompatible ABO blood groups results in rejection mediated by  

 

 

2. Alkylating agent used to eliminate host immune system for HSCT

 

3. Calcineurin inhibitor used in GVHD prophylaxis

 

 

4. What treatment would you give to a patient presenting with rash, vomiting, abdominal pain, diarrhoea, bloody stool and jaundice following HSCT?

 

 

5.  Anti-IL 2 receptor drug inhibiting T-cell interleukin-2 signalling, thereby preventing T-cell proliferation.

 

 

ANSWERS

1. C

2. I

3. G

4. F

5. L