Pathology EMQ template.

Name: Saskia Verhagen      Theme: Autoimmune Disease

 

OPTION LIST

 

A	Ankylosing Spondylitis	I	Hashimoto’s Thyroiditis
B	Churg-Strauss Syndrome	J	Myaesthenia Gravis
C	Crohn’s Disease	K	Pernicious Anaemia
D	Familial Mediterranean Fever	L	Rheumatoid Arthritis
E	Giant Cell Arteritis	M	Sjogren’s Syndrome
F	Goodpasture Disease	N	SLE
G	Graves’ Disease	O	Takayasu’s Arteritis
H	Haemolytic Anaemia	P	Wegener’s Granulomatosis

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A 42-year-old lady presents with extreme fatigue and dark-coloured urine. She also describes some nasal stuffiness and recurrent nosebleeds. Her urine dip shows RBC +++ and serum U&E shows elevated creatinine and urea, as well as a dangerously high potassium. She is admitted urgently to the renal unit at Hammersmith Hospital.

 

2. A young woman has positive serum ANA and anti-dsDNA antibodies. A skin biopsy is taken which shows her skin contains deposits of IgG and complement.

 

3. A Japanese woman presents at her GP, who upon routine examination, cannot locate radial or brachial pulses. The patient reports symptoms of fatigue, night sweats, dizziness and visual disturbances.

 

4. A young Armenian man presents to A&E with acute severe abdominal pain. CRP and WBC are both raised. He stays overnight, sustaining an unremitting fever of 39.5°C.

 

5. A nervous, middle-aged woman presents to her GP complaining of palpitations. As she complains, her GP notices a tremulous grip and protruding eyes.

 

ANSWERS

1. P

2. N

3. O

4. D

5. G