Pathology EMQ template.

Name: Asanka Wijendra

Theme: Immune Therapies

 

OPTION LIST

 

A	Abatacept	I	Methotrexate
B	Azathioprine	J	Mycophenolate
C	Basiliximab	K	Mycophenolate mofetil
D	Cyclophosphamide	L	Natalizumab
E	Cyclosporin	M	Rituximab
F	Denosumab	N	Tocilizumab
G	Efalizumab	O	Ustekinumab
H	Etanercept	P	None of the Above

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Inhibits RANK mediated osteoclast differentiation and function

 

 

2. A 45 year old lady with liver failure awaiting a transplant is given this drug as prophylaxis of allograft rejection. She is also given a dose immediately after the transplant.

 

 

3. Mechanism of action is through the inhibition of Calcineurin

 

 

4. A patient who is known to have a Thiopurine methyltransferase (TPMT) polymorphism is mistakenly given this immunotherapy and goes on to develop bone marrow suppression.

 

 

5. A gentleman has been diagnosed with Castleman’s disease

 

 

ANSWERS

1. F

2. C

3. E

4. B

5. N