Pathology EMQ template

 

YourName: Jonathan Wong Jun Cheong

YourIdentifier:

Theme: Lipoprotein Metabolism

 

OPTION LIST

 

A	Apolipoprotein A	I	LDL
B	Apolipoprotein B	J	VLDL
C	Apolipoprotein C	K	HDL
D	Apolipoprotein D	L	PPAR-α
E	Apolipoprotein E	M	Niacin
F	Apolipoprotein H	N	MCAD
G	HMG CoA reductase	O	VLCAD
H	HMG CoA synthase	P	SCAD

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

 

 

1. A rare genetic condition causes a deficiency of this enzyme. It will typically present at infancy with hypoglycaemia, lethargy and muscle weakness

 

2. A rare genetic condition causes a deficiency of this enzyme. The disease this causes can be managed with proper diet management, most notably the avoidance of fasting

 

3.  This coenzyme is typically associated with the lipoprotein that delivers cholesterol from the tissues to the liver and steriodogenic organs.

 

4. Statins block the action of this enzyme.

 

5.  This coenzyme is typically associate with the lipoprotein that delivers cholesterol from the liver to the tissues

 

 

ANSWERS

1. O (but LCAD is another possible answer)

2. N

3. A

4. G

5. B