Pathology EMQ

Name: LiYan Chow

Theme: Coagulation

 

OPTION LIST

 

A	Acute Idiopathic Thrombocytopenic Purpura	I	Factor VIII
B	Chronic Idiopathic Thrombocytopenic Purpura	J	Factor IX
C	Platelet count <50 x109/L	K	Disseminated Intravascular Coagulation
D	Platelet count <20 x109/L	L	Prolonged aPTT, normal PT
E	Haemophilia A	M	Normal aPTT, Prolonged PT
F	Haemophilia B	N
G	Von Willebrand Disease	O
H	Vitamin K Deficiency	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. 4 year-old boy is brought into A&E with sudden onset purple spots on his legs which do not blanch on pressure. His mother says that he has been unwell for the past 2 days with a cold. The most significant blood test result was...

 

2. A 12 month-old boy’s parents are concerned that their son bruises very easily. On examination it is noted that his knee is very swollen and he refuses to move it. Investigations show that he has low factor VIII.

 

3. A 13 year-old girl visits her GP complaining of very heavy periods. She also reports that she bruises easily and often has nose bleeds.

 

4.   53 year-old gentleman with an advanced cancer develops a high temperature, is tachycardic and has hypotension. The nursing staff have noted that he has been bleeding from venepuncture sites and there is blood in his urine. The most likely diagnosis is...

 

5. On investigation of a patient with Haemophilia A, the blood tests would show...

 

 

ANSWERS

1. D

2. E

3. G

4. K

5. L