Name: Elise Chua                                 Theme: Coagulation

 OPTION LIST

A

Haemophilia A

I

Thrombotic  thrombocytopenic purpura

B

Von Willebrand disease

J

Lupus anticoagulant

C

Vitamin K deficiency

K

 

D

Warfarin Overdose

L

 

E

Liver Disease

M

 

F

Renal Disease

N

 

G

Disseminated Intravascular Coagulation

O

 

H

Autoimmune thrombocytopenic purpura

P

 

 

 

 

 

 

 

 

 

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 50 year old man presents with diarrhoea and weight loss. His history also reveals recurrent ulcers and easy bruising. Coagulation screen reveals prolonged PT and APTT.

2. A 60 year old man presents with fatigue and weight loss of 10kg over 3 months. He is also noted to have developed multiple petechiae. Coagulation screen reveals prolonged PT and APTT, low fibrinogen and thrombocytopenia.

3. A 6 year old boy presents with haemarthrosis after mild trauma to his right knee. Coagulation screen reveals a normal PT, a prolonged APTT, reduced factor VIII clotting activity and normal vWF.

4. A 20 year old woman presents with iron deficiency anaemia. She complains of recurrent nose bleeds and has always had heavy periods. She notes that her mother also suffered from the same problems. 

5. A 30 year old woman presents with left deep vein thrombosis. No obvious precipitating factors are identified in her history. Coagulation screen reveals a normal PT and an elevated APTT of 59 seconds.

ANSWERS

1. C

2. G

3. A

4. B

5. J