Pathology EMQ template.

Name: Katerina Constantinou

Theme: Cytopathology

 

OPTION LIST

 

A	Transclocation t(9;22)	I	NF1 mutation
B	Translocation t(14;18)	J	BRCA1 mutation
C	Translocation t(8;14)	K	Deletion of APC
D	JAK2 mutation	L	Deletion of Rb
E	K-ras mutation	M
F	Trisomy 21	N
G	47 XXY	O
H	CFTR mutation	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1.  A 55-year-old lady presents with a hard lump in her right breast. She has palpable axillary lymph nodes and she is a heavy smoker.

 

 

2.  A 24-year-old Afro-Caribbean man presents to casualty with a big lump in his jaw.

 

 

3.  A 72-year-old man presents to his GP with 3 month history of rectal bleeding. He has lost weight and he feels generally unwell.

 

 

4.  A 45-year-old man presents to his GP with general malaise. His blood count shows a high white blood cell count. Further investigations show that he has the Philadelphia chromosome.

 

 

5.  A 3-year-old boy presents to his GP with vision deterioration. On examination he has leukocoria.

 

 

ANSWERS

1. J

2. C

3. E

4. A

5. L