Pathology EMQ
Name: Harriet Davidson
Theme: Drugs/ Forensic Toxicology
OPTION LIST
|
A |
Alprostadil |
I |
Imatinib |
|
B |
Aspirin |
J |
Isoniazid |
|
C |
Busulphan |
K |
Papaverine |
|
D |
Clofazimine |
L |
Paracetamol |
|
E |
Cyclophosphamide |
M |
Pyrazinamide |
|
F |
Dapsone |
N |
Rifampicin |
|
G |
Ethambutol |
O |
Sildenafil |
|
H |
Ibuprofen |
P |
Thalidomide |
For each scenario, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.
1. A new use for this drug was discovered when it was used as a sedative for a patient with lepromatous leprosy by a physician in Jerusalem in 1964
2. This drug was originally developed as a targeted inhibitor of the Bcr-Abl protein and was subsequently discovered to be effective against a range of other malignancies
3. An effective antipyretic which in overdose can cause hepatocellular necrosis and, much less frequently, renal tubular necrosis
4. A mainstay of TB treatment in the UK that was the first ever anti-depressant
5. Phase I trials in Swansea examining the use of this drug in angina uncovered the importance of the phosphodiesterase 5 enzyme in the helicine arteries.
ANSWERS
|
1. P |
2. I |
3. L |
4. J |