Pathology EMQ template.

Name:Jasmin Hodgson

Theme: Immunodeficiency

 

OPTION LIST

 

A	IFN gamma receptor deficiency	I	Acute lymphocytic leukaemia
B	Lymphocyte adhesion deficiency	J	Drug induced immunodeficiency
C	Chronic Granulomatous disease	K	Immunodeficiency due to malnutrition
D	Kostmann syndrome	L	HIV
E	DiGeorge syndrome	M	Steroid induced immunodeficiency
F	Bare lymphocyte syndrome-type 2	N	IgA deficiency
G	Reticular dysgenesis	O	Simple depletion of comensal bacteria
H	Cyclic neutropenia	P	Meningitis induced immunodeficiency

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A worried mother brings her newborn to A&E after recurrent bouts of diarrhoea and fevers. The blood film showed an absence of neutrophils.

 

 

2. A baby is born with a high forehead, low set abnormally folded ears, cleft palate with a small mouth and jaw. He is found to have T cell lymphopenia despite having normal B cell count.

 

 

 

3. An elderly lady with rheumatoid arthritis presents with a severe episode of diarrhoea after being treated in hospital with broad spectrum antibiotics.

 

 

4. A 4 year old is known to his GP for having suffered with recurrent chest infections and skin abscesses. He has an enlarged liver and spleen and the dihydrorhodamine test is abnormal.

 

 

5. Due to the failure of HLA class II expression.

 

 

ANSWERS

1. D

2. E

3. O

4. C

5. F