Name: Lakshmi Kuhendran

Theme: Metabolic Bone Histopathology

 

OPTION LIST

 

A	Osteocyte	I	Ewing’s Sarcoma
B	Osteoblast	J	Fibrous dysplasia
C	Osteclast	K	Hyperparathyroidism
D	Osteoarthritis	L	Osteoprotegrin (OPG)
E	Osteoporosis	M	Calcium
F	Osteomalacia	N	Phosphate
G	Osteogenesis Imperfecta	O	MAPK
H	Paget’s Disease	P	Vitamin D

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Competes with RANK ligand and reduces bone resorption

 

 

2. Radiological findings may include a horizontal fracture in Looser’s Zone

 

 

3. A deaf 71-year old man presents to the clinic and has a history of recurrent bone fractures. His blood tests show an elevated alkaline phosphatase.

 

 

4. Multinucleate cells that are part of the macrophage family and are involved in breakdown of bone

 

                

5. Characterised by imperfect Type 1 collagen synthesis

 

 

 

ANSWERS

1. L

2. F

3. H

4. C

5. G