Pathology EMQ template.

Name: Robert Ley Greaves

Theme: Myeloproliferative disorders

 

OPTION LIST

 

A	Haemopoetic neoplasm	I	Secondary Myelofibrosis
B	Lymphoid neoplasm	J	Hyper oesinophillic syndrome
C	Chronic Myeloid Leukaemia	K	5q deletion syndrome
D	Primary Myelofibrosis	L
E	Polycythaemia Vera	M
F	Essential thrombocythaemia	N
G	Acute Myeloid Leukaemia	O
H	Chronic Lymphocytic Leukaemia	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Associated with a JAK2 mutation in 20% of cases and MPL mutation in 15%, little increase bone marrow elements other than megakaryocytes

 

 

2. BCR-ABL translocation causes

 

 

3. Cellular phase with increased megakaryocyte size, increased myeloid and erythroid precursors, later fibrotic changes in collagen

 

 

4. Tyrosine kinase inhibitors improve prognosis

 

 

5. Cellular phase with increased megakaryocyte size, increased myeloid precursors, later fibrotic changes in collagen

 

 

 

 

ANSWERS

1. F

2. C

3. E

4. C

5. D