Pathology EMQ template.

Name: Huanghuan Li

Theme: Immune Therapy

 

OPTION LIST

 

A	Interferon alpha	I	Denosumab
B	Interferon beta	J	Etanercept
C	Interferon gamma	K	Plasmapheresis
D	Azathioprine	L	IVIG
E	Bone marrow transplant	M	T-cell
F	Cyclophosphamide	N	Prednisolone
G	Cyclosporin	O	Mycophenolate mofetil
H	Tacrolimus	P	Basiliximab

 

 

For each scenario below, choose the most appropriate treatment from the list above. Each option may be used once, more than once or not at all.

 

1. A female baby was found to have recurrent bacterial, viral and fungal infections, leading to the failure to thrive. Tests on the baby showed that her condition is caused by a deficiency of the enzyme, adenosine deaminase (ADA).  (SCID)

 

 

2. Within the first year of life, a male infant developed recurrent upper and lower respiratory infections. He was also found to have enlarged tonsils, liver, spleen and chronic diarrhea. Tests showed normal numbers of T and B cells. (xlinked lgM)

 

 

3. A 45-year-old Chinese intravenous drug addict went to see his GP for feeling tired for a long period of time. (Hep C)

 

 

4. A 50-year-old Caucasian male was admitted to hospital for haemotypsis and haematuria. He was also found to suffer from sinusitis. Blood test for C-ANCA is positive.  (wegeners’)

 

 

5. A 70-year-old Indian woman suffers from a hip fracture and is now determined to find THE treatment to strengthen her bad bones.

 

 

 

ANSWERS

1. E

2. L

3. A

4. F

5. I