Pathology EMQ

Name: Lydia Lilis

 

Theme: Myeloproliferative disorders

 

OPTION LIST

A	Acute myeloid leukaemia	I	Myeloma
B	Chronic myeloid leukaemia	J	Chronic Lymphocytic Leukaemia
C	DIC	K
D	Essential thrombocythaemia	L
E	Idiopathic Myelofibrosis	M
F	Polycythaemia vera	N
G	Pseudopolycythaemia	O
H	Idiopathic erythrocytosis	P

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A 60 year old male presents with red, painful extremities. He has been previously diagnosed with gout. What is the most likely diagnosis?

 

2. A 55 year old female goes for a routine check-up. On FBC, she has a raised platelet count. What is the most likely diagnosis?

 

3. A 30 year old male with a raised haematocrit comes in for his treatment. He is treated with venesection and sent home.  What is the most likely diagnosis?

 

4. A 70 year old female presents with weight loss, night sweats and shortness of breath. On examination she has massive hepatosplenomegaly. On blood film you see leukoerythroblastic cells. You decide to do a bone marrow trephine to confirm the diagnosis.

 

5. Which disease most commonly results from a JAK2 V617F mutation?

 

 

ANSWERS

1. F

2. D

3. H

4. E

5. F