Pathology EMQ template.

Name: Eve McDermott

Theme: Obesity and Cardiovascular update

 

OPTION LIST

 

A	ABC A I	I	LDL Receptor
B	ABC G5/8	J	MTP
C	Apo A I	K
D	Apo A V	L
E	Apo B	M
F	Apo C II	N
G	Apo E 2	O
H	CETP	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1.  A 10 year old boy presents with corneal arcus and xanthomata. Which inherited mutation is he likely to have?

 

 

2.  A 35 year old man presents to A+E with acute pancreatitis. His blood is found to have raised Triglycerides. Further investigation of his plasma showed formation of a layer of chylomicrons but not of VLDL after refrigeration overnight. This suggests a diagnosis of which underlying deficiency?

 

 

3.  Familial dysβlipoproteinaemia (type III) is associated with yellow palmar striae and eruptive xanthomas on the elbows. This is due to which homozygous polymorphism?

 

 

4.  A Patient presents with enlarged, orange-coloured tonsils due to which mutation?

 

 

5.  Familial Hyperαlipoproteinaemia is associated with which deficiency?

 

 

 

ANSWERS

1.  I

2. F

3. G

4. A

5. H