Pathology EMQ template.

Name: Kapil Patel       

Theme: Primary immune deficiency

 

OPTION LIST

 

A	SCID	I	SLE
B	Chronic Granulomatous Disease	J	CVID
C	Kostmann Syndrome	K	IFN Gamma Deficiency
D	Leukocyte Adhesion Defect	L	C5 Deficiency
E	DiGeorge Syndrome	M	Bruton’s X-linked Hypogammaglobulinaemia
F	C1 Deficiency	N	Bare Lymphocyte Syndrome
G	Hyper IgM Syndrome	O
H	Selective IgA Deficiency	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Condition associated with deletion of chromosome 22q11.

 

2. Deficiency associated with increased susceptibility to atypical mycobacterial infections.

 

3. Classical pathway deficiency is associated with immune complex disease, especially …

 

4. A young man presents to his GP complaining of recurrent chest symptoms. Investigation of phagocyte function reveals absent neutrophils and normal leukocyte adhesion markers.

 

5. Defect of regulatory proteins involved in MHCII gene expression.

 

 

ANSWERS

1. E

2. K

3. I

4. C

5. N