Pathology EMQ template.

Name: Oshini Shivakumar  

Theme: Transplantation

 

OPTION LIST

 

A

HLA DQ

I

Indirect

B

Kidney

J

Liver

C

Acute rejection

K

HLA DP

D

HLA C

L

 

E

Direct

M

 

F

Gut

N

 

G

HLA B

O

 

H

Hyperacute rejection

P

 

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Rejection due to preformed antibodies to the donor antigens, present in the recipient’s serum.

 

 

2. The difference between donor and recipient HLA type is expressed as the number of mismatches at the 3 most important sites: HLA A, HLA DR,  ……..

 

 

3. Allogenic APC and MHC + allogenic peptide, presented to T cell: …………… antigen presentation

 

 

4. Three principal target organs of GVHD: skin, gut, ………

 

 

5. Organ where HLA matching is not used to allocate donor.

 

 

 

ANSWERS

1. H

2. G

3. E

4. J

5. J