Pathology EMQ template.

Name: Andrew D Smith

Theme: Uric Acid Metabolism

 

OPTION LIST

 

A	Allantoin	I	Phenytoin
B	Allopurinol	J	Polarised light
C	Ciclosporin	K	Primary Hyperuricaemia
D	Erythema Nodosum	L	Psoriasis
E	First MTP joint	M	Pyrophosphate crystals
F	Hypoxanthine-guanine phosphoribosyl transferase (HGPRT) deficiency (Lesch-Nyhan syndrome)	N	Renal + Enteral excretion
G	Monosodium Urate crystals	O	Renal excretion alone
H	NSAIDs	P	Secondary Hyperuricaemia

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. What crystals are the cause of acute gout?

 

 

2. Via what route(s) is uric acid excreted?

 

3. Increased adenosine triphosphate (ATP) degradation (e.g. through vigorous muscular exertion) is a cause of what type of hyperuricaemia?

 

 

4. What drug is indicated in first line therapy for acute gout?

 

 

5. Which drug has been associated with increased urate levels?

 

 

ANSWERS

1. G

2. N

3. P

4. H

5. C