Pathology EMQ template.

Name: David Smith

Theme: Uric Acid

OPTION LIST

A	APRT	I	Pseudogout
B	Gout	J	Purine
C	HGPRT	K	Pyrophosphate
D	Hypoxanthine	L	Xanthine Oxidase
E	Lesch-Nyhan Syndrome	M
F	Monosodium Urate	N
G	NP	O
H	Phosphoribosyl pyrophosphate synthetase	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. Which crystals are the cause of pseudogout?   

2. Needle shaped, negatively birefringent crystals are seen under polarised light in which condition?

3. Allopurinol inhibits which enzyme?

4. A 6 month old child has hyperuricaemia and developmental delay. Which enzyme are they deficient in?

5. Overactivity of which enzyme causes primary hyperuricaemia

ANSWERS

1. K

2. B

3. L

4. C

5. H