Pathology EMQ template

Name: Dawn Thompson

Candidate number: 00643249

Theme: Viral Hepatitis

 

OPTION LIST

A

Anti-HBc (IgM)

I

HBsAg with anti-HBe

B

Anti-HBe

J

HBsAg with anti-HBs

C

Anti-HBs

K

HBsAg with HBcAg

D

HAV-DNA

L

HBsAg with HBeAg

E

HBcAg

M

HBV-DNA

F

HBeAg

N

HCV-DNA

G

HBeAg with anti-HBs

O

IgG anti-HAV

H

HBsAg

P

IgM anti-HAV

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Found in patients with acute hepatitis typically within 2 months of infection and persists in those who go on to become chronic carriers of the disease

 

2. Produced in excess during active viral replication, its presence in serum indicates high infectivity

 

3. Useful for measuring degree of viral replication in patients who are HBsAg-positive

 

4. Present in asymptomatic chronic carriers of Hepatitis B who have normal liver biochemistry and are at low infective risk

 

5. Presence in serum is diagnostic for acute Hepatitis A infection

 

 

ANSWERS

1. H - HBsAg

2. F- HBeAg

3. M - HBV-DNA

4. I - HBsAg with anti-HBe

5. P - IgM anti-HAV

 

For explanation of answers see Kumar and Clark