macdonaldluisa

A 35 year old lady presents with a 2 week history of fatigue, upper abdominal discomfort and yellow skin. On examination there are no signs of chronic liver disease. Blood tests reveal a bilirubin of 235umol/L, ALT of 42IU/L, an AST of 39U/L and ALP of 20U/L. ANA (antinuclear antibodies) and ASMA (anti-smooth muscle antibodies) are positive.

Rank the following diagnoses given this information, putting the MOST LIKELY diagnosis first, and the least likely diagnosis last.

a) Autoimmune hepatitis

b) Gallstones

c)Primary biliary cirrhosis

d) Cholangiocarcinoma

e)Viral hepatitis

Answers: 1.a 2.c 3.e. 4.b. 5.d.