Paediatric Haematology
Ranking Question

A 1 year old boy who presents with multiple bruises, mucosal bleeding and a swollen painful knee, that occurred spontaneously with no history of trauma. His Hb was 122g/, WCC 7x10⁹/litre and MCV 75fl. aPTT is prolonged, bleeding time and PT are normal. Rank the following treatments given this  information, putting the MOST APPROPRIATE treatment first, and the least appropriate treatment last.

A) Clotting Factor VIII concentrate

B) Clotting Factor IX concentrate

C) Desmopressin

D) Fresh frozen plasma and cryoprecipitate

E) IV immunoglobulin

Answers: A, D, C, B, E