Name: Theresa Tran

Theme: Transplantation

 

A

T-cell mediated rejection

I

Xenotransplantation

B

Antibody mediated rejection

J

Combined T-cell mediated and antibody-mediated rejection

C

Graft-versus-tumour disease

K

 

D

Post-transplantation infections

L

 

E

Post-transplantation malignancy

M

 

F

Immunosuppression

N

 

G

Post-transplant lymphoproliferative disorder

O

 

H

Graft-versus-host effect

P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. This is a common complication occurring after a stem cell or bone marrow transplantation. The intensity of this condition is related to the degree of HLA-incompatibility.

 

2.  The major mechanism involved in this immune reaction is the activation of the classical complement pathway by the antigen-antibody complex, leading to formation of the MAC (membrane attack complex).

 

3. A patient with blood group B receives a kidney transplant from a donor with blood group A. What immune reaction is likely to ensue?

 

4. In this Type IV hypersensitivity response, graft function will be compromised and often it is associated with pain over the graft and fever.

 

5.  Kaposi’s sarcoma is an example of this type of condition.

 

1. H

2. B

3. B

4.  A

5. E