Pathology VSA (very short answer) template.

Name: Minaal Khan

Theme: Immune therapies

OPTION LIST: not required

For each scenario below, write down the likeliest answer, which will be one or two words in the space below.

1.  Which immunosupressent is associated with irreversible infertility and is only used when there is no alternative?

2.  Which immunosuppressant binds to CD20 on B cells resulting in B cell depletion

3. Which immunosuppressant blocks T cell migration

4. Calcineurin inhibitors act by blocking which cytokine?

5.  Which 2 immunosuppresants act to inhibit the T cell cycle?

ANSWERS

1. Cyclophosphamide

2. Rituximab

3. Natalizumab

4. IL-2

5.  Azathioprine and Mycophenolate mofetil