Your Name: Andrew Keightley
Theme: Herpes Virus and Retroviruses
OPTION LIST
|
A |
Burkitts lymphoma |
I |
Kaposi’s sarcoma |
|
B |
Chicken Pox |
J |
Keratitis |
|
C |
Cytomegaloviruses |
K |
Primary Genital Herpes |
|
D |
Glandular fever |
L |
Roseola infantum |
|
E |
Herpes Labialis (Cold sores) |
M |
Shingles |
|
F |
Herpes Simplex Encephalitis |
N |
|
|
G |
HHV 6 |
O |
|
|
H |
HHV 7 |
P |
|
For each scenario below, choose the
most appropriate answer from the list above. Each option may be used once, more
than once or not at all.
1. 5 year old boy comes to the GP and shows you small pustules over his face, scalp and trunk, which have progressed from small macules in a matter of hours. The previous day he had a fever, headache and malaise but has now subsided. Virology showed the presence of Varicella Zoster Virus.
2. A 25 year old man with a latex allergy comes into GUM clinic with small grouped vesicles and papules on the shaft and glans of his penis. This was accompanied with severe pain in his groin, buttocks and upper thighs, a fever, and dysuria. Virology showed the presence of an alpha herpesvirus, HHV 2.
3. A 21 year old man came to hospital complaining of severe headache, fever, malaise and a sore throat. On examination he showed cervical lymphadenopathy, especially the posterior cervical nodes, and splenomegaly. Peripheral blood tests showed the presence of lymphocytosis with atypical mononuclear cells. The Paul Bunnell reaction was positive for heterophilic antibiodies.
4. 67 year old man comes to A+E with lesions on the skin, that have a localised unilateral pattern that is concentrated in a dermatomal organisation. The previous days the patient complained of extreme pain in the same area. Virology the presence of Varicella Zoster virus.
5. On your elective in central Africa a 7 year old child comes to your clinic with a large mass on his jaw. You take a biopsy of the lump, which shows EBV positive large cell lymphoma B cells. Histology shows a starry sky appearance (isolated histiocytes on a background of abnormal lymphoblasts). Genetic testing shows the presence of a 14q/8q translocation. The consultant suggests treating with cyclophosphamide and a single dose leads to a spectacular remission.
ANSWERS
|
1. B |
2. K |
3. D |
4. M |
5. A |