Name: Peter Williamson

Theme: Amyloidosis & Sarcoidosis

OPTION LIST

A	Bronchial carcinoma	I	Senile amyloidosis
B	Haemodialysis associated amyloidosis	J	Waldenström’s macroglobulinaemia
C	Hereditary amyloidosis	K
D	Hogkin’s Lymphoma	L
E	Multiple myeloma	M
F	Myeloma associated amyloidosis	N
G	Reactive amyloidosis	O
H	Sarcoidosis	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 35 year old female presents to her GP with unsightly, red, tender lesions on her shins. A subsequent CT scan shows evidence of enlarged glands in the lung hilar region, and nodular shadowing in the right middle lobe.

2. A 60 year old man, currently undergoing treatment for long-standing chronic renal failure, complaining of tingling in his wrist & hand when he wakes in the morning.

3. A 70 year old woman is referred to hospital with signs of peripheral oedema and hepatosplenomegaly. Hospital investigations demonstrate a degree of bone erosion and high levels of circulating kappa uniform light chain.

4. A 32 year old man presents with a painless, enlarged axillary lymph node. Slight hepatosplenomegaly is noted on examination. Whilst the patient denies experiencing any night sweats, weight loss or fevers, bloods on admission show a raised ESR and abnormal liver biochemistry.

5. A 64 year old woman with a history of chronic rheumatological disease presents to her GP complaining of abdominal discomfort – which is found to be due to hepatosplenomegaly. An ensuing liver biopsy stains positive with Congo Red stain.

ANSWERS

1. H

2. B

3. F

4. D

5. G