Name: Shivani Arulanandam

Theme: Anti-virals

OPTION LIST

A	Aciclovir	I	No therapeutics required
B	Aspirin	J	PEG-IFNa + Ribavirin
C	Cytomegalovirus	K	Prednisolone
D	Epstein-Barr Virus	L	Varicella-Zoster Virus
E	Ganciclovir	M	Varicella-Zoster Virus Immunoglobulin
F	Herpes Simplex Virus-1	N
G	Human Herpes Virus-8	O
H	IFNa + Ribavirin	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. An otherwise healthy 4 year old boy presents to his GP with a mild fever of 37.8°C and a papulovesicular rash on his chest. What is the recommended management of this child’s illness?

2. A 42 year old woman who is HIV positive comes in for her check-up complaining of “floaters” in her field of vision. Her most recent CD4 count was noted to be 75. Examination of the fundus reveals haemorrhages and exudates along the vasculature of the retina. What treatment is recommended?

3. Which combination of agents is the most effective currently available therapy for chronic Hepatitis C infection?

4. A 19 year old girl presents to A&E with a 1 day history of an extensive rash on her limbs. She says she has been feeling “under the weather” for over two weeks, with a mild fever and sore throat. She was recently prescribed a course of Ampicillin by her GP for her persistent sore throat. Physical examination reveals cervical lymphadenopathy. Which infective agent is most likely to have caused her illness?

5. The patient in question 4 presents to A&E again a week later with “the worst headache of her life” which came on a few hours ago. She complains of nausea and vomiting, and has notable neck stiffness. Her temperature is now 39°C. What treatment is recommended?

ANSWERS

1. I

2. E

3. J

4. D

5. K