Your Name: Luke Mordecai

Theme: Bone Disease

OPTION LIST

A	Osteogenesis Imperfecta	I	Paget’s Disease
B	Osteoarthritis	J	Osteomalacia
C	Rheumatoid Arthritis	K	Ankylosing Spondylitis
D	Septic Arthritis	L
E	Achondroplasia	M
F	Gout	N
G	Reiter’s Disease	O
H	Osteoporosis	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 30 year old male presents with painful swelling and inflammation of his right foot, especially at the Achilles Tendon; urethritis and conjunctivitis are also diagnosed.

2. An 80 year lady presents complaining of pain on movement and stiffness after inactivity in her legs, most notably in her hips and knees. She also complains of pain in her hands and marked symmetrical swelling is noted in her DIP joints.

3. A 65 year old woman suffering from Coeliac disease presents with a painful hip which is subsequently diagnosed as a spontaneous fracture of the pelvis. She also complains of generalised bone pain and on examination is noted to have weakness of the proximal limb muscles. It is found that her serum calcium is decreased whilst her ALP is higher than the normal range.

4. A single gene, autosomal dominant disorder affecting the fibroblast growth factor receptor. Patients presenting with this condition have characteristic short limbs, especially the proximal portion of the arms, along with a pronounced lumbar lordosis, prominent forehead and depressed nasal bridge.

5. A five year boy presents to the fracture clinic for the tenth time in his life. The majority of his fractures have been of a spontaneous nature. It is also noted that the uveal pigment of his eye is visible through the sclera which strangely appears blue.

ANSWERS

1. G

2. B

3. J

4. E

5. A