Pathology EMQ template.

Name:Shivani Jaiswal

Candidate number:

Theme:Retroviral Infection

 

OPTION LIST

 

A	DNA Polymerase Inhibitors	I	Pyrimidine Analogues
B	Folate Inhibitors	J	Topoisomerase Inhibitors
C	Fusion Inhibitors	K
D	Integrase Inhibitors	L
E	Non-nucleoside Reverse Transcriptase Inhibitors	M
F	Nucleoside Reverse Transcriptase Inhibitors	N
G	Protease Inhibitors	O
H	Purine Analogues	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Zidovudine is a drug used in the treatment of HIV. What class of drug is it?

 

 

2. This class of drug is used in the treatment of HIV and its mechanism of action is to block the cleaving of viral proteins.

 

3. The HAART combination therapy includes 3 drugs. 2 are nucleoside reverse transcriptase inhibitors and the third is either a protease inhibitor or which other type of drug?

 

4. Which class of drug prevents the docking process of the HIV virus to the host cell?

 

5. In order for HIV proteins to be formed, the viral genome needs to be inserted into the host genome. Which class of drug inhibits this step?

 

ANSWERS

1. F

2. G

3. E

4. C

5. D