Pathology EMQ template

 

YourName: Kirushanthi Rajanayagam

YourIdentifier: kr100

Theme: Porphyrias

 

OPTION LIST

 

A	Spleen	I	Kidney
B	Haem	J	Acute intermittent porphyria
C	Brain	K	Uroporphophyrinogen III synthase
D	ALA synthase	L	Porphobilinogen deaminase
E	Uroporphyrinogen decarboxylase	M
F	Porphyria Cutanea Tarda	N
G	Liver	O
H	Protoporphyrinogen oxidase	P

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Which enzyme is deficient in Porphyria Cutanea Tarda?

 

 

2. Which form of Porphyria presents with neurovisceral manifestations only?

 

 

3. What enzyme is deficient in Acute Intermittent Porphyria?

 

 

4. What causes negative feedback inhibition in the haem biosynthetic pathway?

 

 

5. What is the principal site of enzyme deficiency in porphyria?

 

 

ANSWERS

1. E

2. J

3. L

4. B

5. G