Pathology EMQ template

 

YourName: CHOTAI Neil

YourIdentifier: 00394300

Theme: COAGULATION

 

OPTION LIST

 

A

Gamma glutamyl carboxylase

I

Prothrombinase

B

Factor 7

J

Streptokinase

C

Factor 8

K

Thromboxane A2

D

Factor 9

L

Tissue Factor

E

Factor 10

M

Tissue Plasminogen activator

F

Plasmin

N

Vitamin K Carboxylase

G

Prostacyclin PGI2

O

Vitamin K epoxide reductase

H

Protein C/ Protein S

P

Von Willebrand Factor

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1.  Which clotting factor is considered to be low in Haemophilia A?

 

 

2.  This clotting factor is considered to be low in Haemophilia B?

 

 

3.  Warfarin acts by inhibiting the actions of a particular enzyme which increases the amount          of Vit K . What is this enzyme?

 

 

4. Factors such as 2, 7, 9 and 10 can only be synthesised when their precursors have their glutamic acid residues carboxylated to allow the factors to bind phospholipd on the vascular endothelium. What enzyme is required for this process?

 

 

5. In the Arachidonic acid pathway this particular substance induces platelet aggregation.

 

 

ANSWERS

1. C

2. D

3. O

4.  N

5. K