Pathology EMQ template.

Name: Richard Kirkdale

Candidate number:

Theme: Immune Therapy

OPTION LIST

A	Azathrioprine	I	Rituximab
B	Cyclophosphamide	J	Tacrolimus
C	Dexamethasone	K
D	Efalizumab	L
E	IFN-α	M
F	IFN-γ	N
G	Infliximab	O
H	Mycophenolate mofetil	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. Macrolide antibiotic which decreases clonal proliferation of T-cells through inhibition of IL-2 gene transcription

2. Widely used Anti-TNF-α-Antibody

3. Highly toxic causing bone marrow suppression in patients with specific TPMT polymorphisms

4. Licenced for use in the treatment of chronic granulomatous disease

5. DNA alkylating agent

ANSWERS

1. J

2. G

3. A

4. F

5. B