Annie Movsesyan

CID : 00412796

Theme: Multiple Myeloma

A	Amyloid	I	Ig G
B	Chronic Myeloid Leukaemia	J	Hodgkin’s Lymphoma
C	Waldenstrom’s Macroglobulinaemia	K	Multiple Myeloma
D	CRP	L	Free light chains
E	Paraprotein levels	M	IgM
F	IgA	N	Serum Albumin
G	Beta-2 microglobulin	O	Renal Function
H	Acute Lymphoblastic Leukaemia	P	Calcium levels

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. In order to confirm the diagnosis of Multiple Myeloma, the serum and urine are screened by immunoglobulin electrophoresis for paraproteins. What is the most commonly occurring paraprotein in this condition?

2. A 62 year old man presents with bone pain of the ribs and back. Number of investigations were carried out. Results found raised ESR, urinary Bence-Jones protein and reduction in normal polyclonal Igs. Also, lytic lesions were seen on X-ray. What is the likely diagnosis?

3. Repeated intravenous or oral chemotherapy cycles such as cyclophosphamide, dexamethasone and Thalidomide (CDT), Cyclophosphamide, Vincristine, Adriamycin and Dexamethasone (CVAD) may be used in the treatment of which condition?

4. A condition in which there is a lymphoplasmacytoid lymphoma which produces a monoclonal IgM paraprotein.

5. The most important predictor of prognosis of Multiple Myeloma.

1. I

2. K

3. K

4. C

5. G